Billionaire Stanley Druckenmiller just let go of his stake in Microsoft (MSFT) while pouring millions of dollars into a bet on e-commerce, AI and robotics.
A new 13F filing shows Druckenmiller’s Duquesne Family Office has opened a new position in Amazon (AMZN) in the third quarter, acquiring 437,070 shares valued at $95,967,000 as of September 30th.
The fund completely exited its Microsoft Corp. holding, selling all 200,930 shares previously owned, valued at $100 million as of June 30, 2025.
Duquesne also bought 102,200 shares worth about $24.8 million of Alphabet (GOOGL) and 76,100 shares worth $55.9 million in Meta (META), while selling all 100,675 shares of Eli Lilly (LLY) worth $78.5 million.
The total portfolio value stands at $4.06 billion, with top holdings including 3,214,532 shares worth $517 million of Natera (NTRA) and 2,423,435 shares worth $349 million of Insmed (INSM).
Druckenmiller, a former hedge fund manager for George Soros, is known for bold bets, with his moves often signaling market trends, especially in tech.
Druckenmiller has had remarkable success over the years, and is known for sending Duquesne Capital to an average annual return of 30% for three decades without a single losing year.
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